Boston-Cambridge Careers Data Science Gene Therapy Genomics Healthcare & Life Sciences Oncology

Scientists – Cell Therapy

Cambridge, MA

Job Responsibilities

  • Perform cellular biology workflows on primary cells (cell culture including isolation, maintenance and differentiation of primary B cells, flow cytometry, protein quantification, and other molecular biology techniques)
  • Engineer therapeutic B cell products including site-specific genome editing in primary B cells (designing & using appropriate genome editing techniques including cell electroporation and viral vector design)
  • Supervise and participate in the design, construction and testing of functional therapeutic proteins for engineered cells in cell assays and in preclinical models, including reagent design and procurement
  • Troubleshoot and innovate around proprietary protocols
  • Provide assistance in establishment and utilization of pre-clinical models

The position involves hands-on experimental cellular and molecular immunology and will require the applicant to draw on diverse knowledge and experience to design and execute experiments in the laboratory.

Position Requirements

  • Ph.D. degree in Biological Engineering, Biomedical Engineering, Immunology, or closely related field with a track record of substantial research accomplishments
  • 1-4 years relevant experience in biopharmaceutical or biotechnology industry with a role in cellular engineering (title commensurate with experience)
  • Demonstrated record of scientific achievement (strong publication and/or patent record)
  • Proven ability to establish and troubleshoot molecular biology techniques
  • Experience with ex vivo cellular engineering is strongly preferred
  • A deep understanding of conventional immunological techniques with extensive experience with primary cell culture (including primary B cells) and cell-based assays
  • Ability to work efficiently both independently and in a team environment
  • Scientific creativity, critical thinking, ability to innovate, and analytical problem solving
  • Experience in project management and excellent communication skills

qualified candidates should send Resume or CV to