CSO-COO Rare Disease Platform

We have developed biological insights that suggest how specific enzyme loss leads to disease and potential strategies for replacing its activity. These discoveries also uncovered pathways where the enzyme intersects with cancer and other neurodegenerative diseases. We will leverage this knowledge to develop therapies for common and rare diseases. 

Senior Vice President

We aim to translate the genetics of the immune system to create clinical products to improve the way in which diseases are both diagnosed and treated. We have a robust clinical pipeline that leverages our partnership with Microsoft to use machine learning to accelerate our ability to connect receptors and antigens to enable our vision for the early and accurate detection of many diseases at the same time.  

for more information on this role and to apply, please contact us jobs@tseworldwide.com

Global Sales and Marketing – Healthcare

Coming Soon…

Executive Level Sales and Marketing – Commercial Launch

For a preview discussion, please contact me tsharon@tseworldwide.com

Bay Area Biotech – COO or CBO

Bay Area Biotech seeded through 2021 with full Gene Therapy development team is seeking a COO or CBO

Ideal candidate has deep scientific background, preferably a PhD and has helped scale biotech business through early iterations. Alternative is successful strategy/management consultant with operating experience ready to take on this amazing leadership role.

For a full discussion, please email tsharon@tseworldwide.com

CSO/Head of Discovery AutoImmune Rare Disease

Head of R&D – Rare Disease,  San Francisco or Redwood Shores, CA

Job Description

The Chief Scientific Officer (CSO) will lead our research programs from hypotheses to clinical trials. The CSO will lead all preclinical activities (discovery, development, etc.)



  • Evaluate current therapeutic avenues under investigation  and conceive of additional options to pursue, then contribute to program selection
  • Establish clear expectations and priorities and drive key initiatives to completion
  • Guide preclinical R&D for multiple programs
    • Plan research activities so they enable Investigational New Drug (IND) submission
    • Work with internal members and outside contractors to prepare research protocols
    • Analyze and interpret data, then advise on follow-up studies
  • Oversee preparation and submission of patent applications


  • Lead IND through NDA (New Drug Application) submission processes
  • Interact with regulatory authorities and advisors to facilitate safe and rapid translation of preclinical research to clinical trials
  • Design clinical research study protocols, including objectives, patient inclusion/exclusion criteria, dose selection, endpoints, sample size, and safety monitoring
  • Interpret results from clinical trials and guide future trials
  • Maintain knowledge of treatment landscapes including current treatment strategies, current and potential competitors, and new therapeutic developments


  • MD, PharmD or PhD in the life sciences with at least 10 years of pharmaceutical or biotechnology industry experience in clinical drug development
  • Comprehensive understanding of the drug development process in all phases of testing
  • Strong scientific background, exemplified by publications and overall stature in the pharmaceutical/biotechnology industry
  • History of leading teams from discovery to clinical stages
  • Extensive experience designing, running, and managing multiple pre-clinical programs simultaneously
  • Track record of successful IND submissions and experience interfacing with regulatory agencies
  • Significant experience in designing and carrying out clinical trials
  • Experience in drafting patent applications and moving them through to issuance
  • Ability to consider new information outside of his/her area of expertise
  • Excellent communication, organizational, and interpersonal skills

Not required, but desired

  • Experience in gene therapy, enzyme replacement therapy, or gene editing
  • Experience in developing treatments for rare diseases and/or neurodegeneration

Please email CV and Cover Letter to jobs@tseworldwide.com

Executive Director, Late Phase Medical Lead

Executive Director, Late Phase Medical Lead

Position Summary

The Executive Director , will provide global support for strategic planning and leadership in our metabolics program for Rare GI. He/She will be responsible for providing strong scientific and medical support with an in-depth understanding of the Metabolics medical landscape, particularly in the designated therapeutic areas. He/She will also support the development and implementation of the short and long-term strategy, practices and infrastructure for Global Activities, aligning with overall medical affairs strategy and effective cross-functional collaboration, namely on the development of phase IIIB/IV research, Advise seeking activities, Patient Engagement, Materials, etc. Support the Global Medical Affairs mission to maximize patient outcomes by setting and continuously advancing the evidence-based medical standard of care.

Job Duties & Responsibilities

Develop and implement global medical strategy and plan for GMA activities (pre-launch and post -launch as applicable) for the Metabolics by providing medical leadership, insight and strategy to the global medical affairs team across functions and countries globally. Responsible for the following:

  • Develop in-year global medical strategy, Implementation and budget plan for global initiatives
  • Lead on the situational assessment and the global product strategy development including harmonization of activities involving KOLs.
  • Provide medical strategic recommendation for in-line life cycle management (LCM) and late phase pipeline programs
  • Development and execution of major registration LCM program and geographically expansion strategy
  • Develop Phase 3b/4 and ISR evidence generation strategy for late phase pipeline and in-line TA programs
  • Develop and oversee clinical study design (non-registration phase IIIb/IV, registries, outcomes research etc.) for late phase pipeline and in-line Metabolics programs in close collaboration with relevant functions
  • Provide medical review and ensure alignment with Metabolics strategy of Investigator sponsored research (ISR) proposals including the review of the Final Report
  • Provide clear strategic guidance to scientific communication, internal medical training, external medical education (CME, Symposia, medical education), Medical info, PEVT teams in developing functional plans supporting global medical strategy
  • Develop medically appropriate commercial strategy/tactic, planning and execution
  • Provide global medical guidance to country medical teams in developing country medical plans aligned with global medical strategy
  • Collaborate with country medical Metabolics lead to ensure local activities are aligned with global medical strategy and that Global Medical is sufficiently aware of country insights and needs. Alignment among Global and Country Medical Plans, adjust if needed.
  • Monitor team performance in terms of goals and delivery of global medical plans
  • Serves as the medical expert and resource within ALXN in support of the therapeutic area.
  • Lead content development and presentation for external medical education programs, and other Global Medical initiatives
  • Develop, conduct, or participate in therapeutic training programs for personnel.
  • Medical affairs review materials
  • Independent review of Medical Grant requests including CME, symposia and others.
  • Medical affairs review of post approval regulatory responses and annual safety reports
  • Medical affairs review of reimbursement and value dossiers
  • Medical affairs review of congress abstracts and publications
  • Establishes strategic partnerships with centers of excellence and KOLs in areas of scientific interest and serves as conduit for flow of information both out to the medical community and into the company. Responsible for the following:
  • Development and execution of Global KOL medical engagement strategy
  • Provide Metabolics KOL engagement strategy and guidance to country medical teams in developing country KOL engagement plans
  • Establish and/or enhance partnerships with key academic institutions and develop relationships with global key thought leaders
  • Planning, designing and managing global medical Advisory Boards and gather insight from regional/local medical Advisory Boards
  • Responsible for the Global and Country Quarterly Management Review and will be consulted on defining Country-Specific Medical Plan.

Essential Qualifications

  • Disease and Product Expertise (preferably with background on Neurology, Endocrinology, Hepatology or Internal Medicine)
  • Experience leading Medical Affairs function
  • Proficient in Medical Governance and operations, with extensive regulatory and compliance experience leading a Medical Affairs organization
  • Strong people management and leadership skills acquired in a multicultural environment
  • Excellent communication skills both written and verbal.
  • Ability to lead and motivate a team, both internally and remotely
  • Excellent interpersonal skills with demonstrated track record and ability to drive results as an effective a team member and project leader
  • Previous Clinical Operations experience (design and implementation of clinical trials)
  • Proven ability to manage budget and resources
  • Strong business acumen
  • Ability to build partnership access between HQ and affiliates
  • Flexibility and ability to adapt to changing conditions
  • Excellent problem solving, organizational, and negotiating skills
  • Must demonstrate an energy and enthusiasm which brings a positive approach to all challenges Sense of ethics and responsibility
  • Fluent in English
  • Travel required up to 25% to 35%

Preferred Qualifications

  • Scientific and technical acumen in Neurology, Hepatology, Gastrenterology, Lipidology and/or Bone Metabolism
  • Fluency in Spanish or Portuguese is a plus
  • Health Outcomes Research/Reimbursement Experience
  • Regulatory Affairs
  • Clinical Development Experience


  • Must have a MD, PhD or PharmD level degree or equivalent
  • 3 years + experience in medical affairs/R&D organization ( Development, Phase IIIB/IV, med info, grant processing, ISR review, field Experience, Global KOL management, scientific communications & publications)
  • Experience leading cross-functional teams
  • Experience managing people
  • Experience in the Pharmaceutical or biotechnology industry

please email CV and cover letter to jobs@tseworldwide.com for consideration

Vice President, Process Development; Cellular Assays

Position Overview:

The Vice President (VP) of Product Development will be responsible for state-of-the art cellular immunology laboratory process and product development requirements. This key role will lead the transition of T-cell receptor (TCR) discovery workflows from research and proof-of-concept to the next product development stage. The VP of Product Development is accountable for implementing end-to-end TCR screening and characterization workflows, assay validations and standardization. S/he will implement GLP-compliant processes, production-level controls, drive assay / method validations, maintain all necessary documentation, and evaluate workflow changes that could affect the production and control of a TCR product. The VP of Development will put in place strategies to scale cellular immunology laboratory and support the development of IND-ready products.  This key leadership role will support corporate-level Drug Discovery goals.

Job Responsibilities:

  • Evaluate current cellular immunology and workflows, assays (e.g., TCR binding, cell killing and safety) and processes. 
  • Transition research-based workflows into product and process development under GLP conditions. 
  • Lead product development strategy and establish TCR product validation and development plans, including product characterization and safety evaluation. 
  • Maintain relevant requisite TCR screening and product controls plus validation data. 
  • Develop and maintain detailed reports containing TCR screening and characterization development methods. 
  • Lead efforts to inform the development of real-time, patient-specific TCR screening process for a future fully personalized TCR-based cellular therapy. 
  • Coordinate cross-functionally with R&D, Operations and leadership to provide timely product development needs that inform infrastructure or resource requirements.

Experience and Skills:

  • Advanced degree in Life Sciences: PhD, MD, or MD / PhD. 
  • Strong background and experience in biologics process validation and product development. 
  • Experience in cellular immunology / biology is preferred. 
  • >7 years of experience leading product development. 
  • Demonstrated understanding of assay and product development requirements. 
  • Ability to work in a matrix environment and leverage cross-functional resources. 
  • Ability to function autonomously and drive strategic decisions. 
  • Team leader with the ability to work and manage others. 
  • Ability to work effectively with senior-level stakeholders, internally and externally. 
  • Strong communication and interpersonal skills and good judgment. 
  • Independent strategic thinker with strong ability to solve complex problems. 
  • Excited about an early stage company environment and driven to make a difference.

Sr. Director/VP – Cell Therapy Discovery

Position Overview:

The Sr. Director of Cell Therapy Development will be responsible for establishing therapeutic product requirements and develop IND-enabling strategies for our Drug Discovery group. The Sr. Director of Cell Therapy Development will develop, plan and implement product requirements to inform clinical programs for T cell receptor based cell therapies plus any potential future drug modalities to be developed. S/he will establish product efficacy and safety specifications. In the near-term, this role will focus on informing robust TCR data packages for IND submissions and IND-enabling clinical trials.

This key role within R&D will guide the cellular therapy product development strategy and successfully enable us to achieve its Drug Discovery clinical development goals.

Job Responsibilities:

  • Lead IND-enabling strategy and establish TCR-based cellular therapy development plans. 
  • Inform clinical Target Product Profile (TPP) and develop IND-enabling TCR data packages. 
  • Support R&D efforts to ensure the creation of comprehensive product development plans. 
  • Support communications to fulfill regulatory authority requirements and address inquiries (e.g. Pre-IND meetings, IND questions and answers). 
  • Lead the development of product characterization; maintain relevant requisite product controls. 
  • Develop reports to support regulatory submissions/filings. 
  • Track and report any significant changes to the TCR discovery process / methods that may require amendments to regulatory materials or impact future manufacturing process and product development. 
  • Lead efforts to inform framework for real-time, patient-specific TCR screening, including immune monitoring during clinical trials. 
  • Provide timely product development requirements that inform new product/clinical needs. 
  • Write and implement development protocols, review and interpret data.

Experience and Skills:

  • Advanced degree in Life Sciences: PhD, MD, or MD PhD. 
  • Strong background and experience in biologics product development. 
  • Experience in cellular immunology/biology and cellular therapy product development. 
  • >5 years of experience leading biologics product development. 
  • Demonstrated understanding of IND-enabling product requirements and product launch. 
  • Ability to work in a matrix environment and leverage cross-functional resources. 
  • Ability to interact strategically with drug discovery partners to inform product requirements. 
  • Ability to function autonomously and drive strategic decisions. 
  • Team leader with the ability to work and manage others. 
  • Ability to work effectively with senior-level stakeholders, internally and externally. 
  • Strong communication and interpersonal skills and good judgment. 
  • Independent strategic thinker with strong ability to solve complex problems. 
  • Excited about an early stage company environment and driven to make a difference.


I am working with select VC backed, post Series A biotechs on opportunities in Boston/Cambridge and the Bay Area. Opportunities for CBO, COO and CFO (or hybrid) and Investor Relations. Ideal backgrounds include M&A, Investment Banking, Equity Research and Sr Strategy Consulting. Please let me know If you are considering an operating role in 2020 and send message to tsharon@tseworldwide.com to set up a conversation

Director, Global Marketing, -Neuromuscular

Director, Global Marketing, -Neuromuscular (Location Open)

We are recruiting for the position of Director, Global Marketing, Neuromuscular who will be responsible for the development and execution of Global marketing strategies and tactics for our portfolio.

Reporting to the Therapeutic Area Lead, the Director will be in a critical position working cross functional teams, regional, country and corporate leadership and to advance care in the rare disease community and drive commercial success.

The Director, Global Marketing ensures adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.

Job Description:

ESSENTIAL FUNCTIONSPrimary duties/responsibilities:

  • Assists in the development and execution of the Global strategic and tactical plan
  • Ensures strategic alignment between the Global strategic and tactical plan with the regions and countries
  • Develops the Global communication platform including key elements of positioning, messaging, value proposition, creative campaign, and promotional pieces
  • Creates and implements global educational initiatives (e.g. symposia, speaker’s bureau, stand-alone events) to raise disease awareness, increase patient identification, and drive belief in Translarna and Emflaza
  • Plans and executes HCP and patient market research and advisory board meetings to gain actionable market and customer insights
  • Works cross functionally to identify and partner with global KOLs
  • Understands the challenges and growth opportunities in the rare disease community and translating these into marketing initiatives
  • Plans and executes global congress activities
  • Manages external agencies to ensure execution of marketing programs aligned with brand strategy objectives
  • Ensures timely and efficient review of promotional materials and complying fully with all legal, regulatory, ethical, and company guidelines
  • Works with stakeholder partners in Medical Affairs, Marketing, Market Access, regional and country leadership, Distribution and Finance to optimize commercial success for the near term and future product launches
  • Leads a culture of compliance, integrity and transparency
  • Manages the operating budget(s) and initiating corrective measures as appropriate
  • Performs other tasks and assignments as needed and specified by management

KNOWLEDGE/SKILLS/ABILITIES REQUIREDMinimum level of education and years of relevant work experience.

  • 7 + years of experience in Global Marketing or other relevant functions
  • Launching and managing products globally in complex rare disease markets
  • Minimum of Bachelor’s Degree; Master in Science or MBA preferred

Special knowledge or skills needed and/or licenses or certificates required.

  • Demonstrated track record of success supporting the marketing and commercialization of an orphan, rare disease and/or specialized drug(s) that requires the development and execution of unique sales and marketing strategies.
  • Demonstrated success in developing and executing long term and annual marketing plans.
  • Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members
  • Analytical thinker with strong problem-solving skills and the ability to adapt to changing priorities and deadlines. 
  • Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects. 
  • Ability to anticipate issues and respond quickly, flexibly and creatively to solve problems and address commercial market challenges
  • Hands-on experience in collaborating and working with patient organizations.
  • Ability to influence without direct authority.
  • Proficiency with Microsoft Office
  • Excellent verbal and written communication and skills.
  • Fluent in English (verbal and written).

to apply please send resume and cover letter to jobs@tseworldwide.com

Head of Developmental Sciences – San Diego

The Developmental Sciences Department is dedicated to strategies that bridge preclinical research and clinical development. Reporting to the CMO, this position will lead a team of scientists and/or physicians in defining and implementing translational initiatives. The incumbent will work cross-functionally to establish and implement research collaborations with other functional areas within the Company including clinical pharmacology, predictive biomarkers, pharmacodynamic biomarkers, and pharmacovigilance. This work will impact project level decision making and will require effective communications across a broad range of constituencies.

Key Responsibilities

  • Work with Team members and key partner functions (including Regulatory, Commercial, Nonclinical Development, etc.) to define biomarker strategies
  • Oversee the discovery and development of development and provide guidance to potential partners for co-development of companion diagnostics 
  • Collaborate with colleagues in research and other departments to advance internal research and early development projects 
  • Manage, mentor, advise and foster the career development of a diverse group of development sciences team professionals
  • Contribute to the Translational Medicine Team’s mission to understand the mechanism(s) of action 
  • Provide Translational Medicine support to partner functions; this may include providing input into clinical protocols, informed consents, sample collection manuals, investigator brochures and regulatory documents; helping to resolve biomarker-related questions from regulatory agencies; reviewing and interpreting clinical study outcomes, and overseeing the presentation of relevant results in clinical study reports and other study documents 
  • Maintain a strong understanding and awareness of emerging medical and diagnostic developments 
  • Develop models, both preclinical and clinical, to ensure robust decision making on developability of drug molecules in various therapeutic areas of interest
  • Design proof of concept studies and full development for various therapeutic area programs
  • Contribute to and review the clinical section of documents including, but not limited to, Protocols, the Investigator Brochure (IB), Case Report Forms (CRFs), Annual IND Safety Updates/EU Annual Reports, Clinical Study Reports, patient narratives, and submission related documents such as the Clinical Summary of Efficacy and Safety and the Clinical Overview

Education & Experience

  • A minimum of an M.D. or Ph.D. with at least 10 years drug development experience in a biopharmaceutical environment 
  • Demonstrated experience in development, implementation and execution of clinical development strategies for novel drug candidates, from preclinical development through clinical proof-of-concept 
  • Successful track record with biomarkers in the clinical space including development and implementation of biomarker strategies required 
  • Hands-on experience establishing clinical, molecular and cellular diagnostics 
  • Working knowledge of GCP and FDA regulations 
  • Advanced knowledge of immune-oncology and emerging therapies in oncology. 
  • Detail-oriented with the drive and ability to prioritize workload with limited supervision 
  • Strong interpersonal skills and the ability to function in a team environment 
  • Excellent written communication and oral presentation skills 
  • Phase 3 clinical development experience desired

to apply please send resume and cover letter to jobs@tseworldwide.com

Associate Director, Program Management – Gene Therapy

Associate Director, Program Management – Gene Therapy

Summary of Position

The Associate Director, Program Management will support preclinical and/or clinical programs. The Associate Director will be responsible for driving strategy and cross-functional execution on key program work streams, as well as for managing overall program timelines and budgets to support achievement of relevant corporate and program milestones. This role will contribute to the development plan and budget for the franchise.  In addition to these preclinical/clinical program responsibilities, the Associate Director, Manager of Program Management will help support the Head of R&D Program Management with other initiatives as needed, and will contribute to strategic projects across the R&D program portfolio such as portfolio planning, due diligence, and long-term planning.

Roles and Responsibilities

  • Working closely with the Head of R&D Program Management and Discovery area leaders to manage development and execution of overall global strategy for the preclinical programs
  • Contributing to timely execution of program activities including anticipating and identifying project risks, mitigations and contingencies, and supporting timely action plans and issue resolution
  • Ensuring effective communication to align program activities with corporate strategy, and ensure effective program execution
  • Partnering with functional team members to monitor program spend against budget, and to develop project scenarios for decision making
  • Using key project management tools to enhance project and program delivery and information dissemination to the team and key stakeholders
  • Ensuring effective program team meetings, logistics and documentation
  • Contributing to development and review of corporate communications
  • Supporting other initiatives as needed
  • Contributing to strategic projects across the R&D program portfolio such as portfolio planning, due diligence, and long-term planning.

Qualifications and Background Requirements

  • A degree in the life sciences is desirable
  • An advanced degree in the life sciences, MBA or management consulting experience is desirable
  • Formal training in program/project management (e.g. PMP certification) is a plus
  • 6+ years of development experience in the pharmaceutical/biotech industry (with drug substance/drug product manufacture, preclinical, analytical, quality, clinical, and/or regulatory), of which 3+ years in program management
  • Strong interpersonal and communication skills for effective collaboration
  • Solid organizational skills including high attention to detail and ability to multi-task
  • Strong business acumen
  • Previous project management experience
  • In-depth experience with project management tools

Please email resume & cover letter to jobs@tseworldwide.com

Executive Director, Rare Disease Product Development

Executive Director, Product Development, Bay Area

Product Development is responsible for corporate and R&D governance, business operating model (core teams and sub-teams) and portfolio strategy. Product Development integrates overall product strategy and ensures planning and timely execution to inform decision making and development of therapies .


Product champion and leads a team of core functional leaders that together help develop product strategy and planning for clinical and/or marketed products. You will be the primary liaison between team/sub-teams and executive management and has overall accountability to executive management (CEO and CEO leadership team) for the integrated product strategy. In collaboration with core team (CT) members, ensures progress and execution against plans and as the leader of the CT is the primary contact for internal stakeholders. As a senior leader in the core team leader group, is a role model, mentors peers and contributes to key core team processes and initiatives.

Key Responsibilities:

Program Strategy
Lead the CT in the generation of a Target Product Profile and the cross-functional compound development and lifecycle strategy taking into account global considerations
Lead CT and develop forward looking integrated stage based product development plans that are aligned with program strategy and ensures assumptions and drivers are aligned with plans to inform financial planning
Lead efforts in partnership with line functions to optimize value of the compound throughout its lifecycle.
Ensure potential risks are identified and contingency planning with a solutions focused mindset.
Team Effectiveness
Ensure cross functional partnerships and resources are leveraged effectively, and with accountability, to achieve program objectives.
Drive collaboration and transparency across all functions on the CT and challenge team members to be broad and inclusive in their strategy planning.  
Resolve conflicts at the Core Team, provide and receive feedback to develop and maintain a high performing team and if necessary escalate team member performance related issues to functional management
Governance and Approvals
Ensure that team recommendations are brought to appropriate governance for management buy-in and decisions
Ensure alignment of program strategy/plan/execution with management expectations & priorities
Lead CT in the development of scenarios and recommendations and present CT position for decision making at various governance bodies. Leverage SMEs for expertise and have SMEs present on topics pertaining to their areas
Single point of contact on program for executive and functional management
Ensures communication of rationale and context for decisions made to team
Leads team in developing a comprehensive internal and external communication plan with team input for important program milestones, key data, etc.
Reviews and agrees to publication plan, reviews publication concepts, presentations and manuscripts
Primary source for information as needed for external communications (press releases, investor related, etc.)
Reviews health authority related documents and ensures consistency with strategic objectives for the program
In partnership with Project Management Lead, CTL ensures
Timely progress and execution against strategy and plans
Timely and aligned input into drivers for LRP and Budget process


The successful candidate will ideally have an advanced degree in a scientific discipline (e.g., Ph.D. or M.D.); M.B.A. is a plus.


15+ years (Executive Director) or 12+ years (Senior Director) experience in the biotechnology/ pharmaceutical industry. Ideally, the individual will have experience in drug development across several therapeutic areas and across the spectrum of drug development and life cycle management.
Experience as a leader of product or compound strategy teams or sub-teams. Experience leading a core/cross functional strategy team for an investigational therapy through development is preferred.
The successful candidate will also demonstrate strong leadership ability and professional credibility to influence a highly intelligent and sophisticated audience of colleagues, partners, and external constituents.
This individual must be a self-starter and possess excellent leadership, influencing and communication skills, as they will be applied at all levels, including at the core team, interactions with the executive team, and presentations to high-level internal and external audiences

Head of Regulatory – Gene Therapy -NJ/Boston/San Francisco


Reporting to the Chief Development Officer the successful candidate will:

  • Act as the regulatory lead on specific program(s) and represent the regulatory function on related cross-functional program teams
  • Participate in definition and implement regulatory strategy for path to approval
  • Plan, prepare, and review submissions to regulatory authorities (including FDA, EMA and other national authorities) to support the conduct of clinical trials and approval of marketing applications (IND, CTA, BLA, MAA)
  • Lead regulatory activities for assigned projects in line with US, European, ICH, and other applicable requirements to ensure compliance
  • Manage the regulatory aspects of products and projects including achievement of timelines and deliverables
  • Ensure that regulatory documents are accurate, complete and verifiable, and confirm compliance with regulatory requirements
  • Be the primary liaison with regulatory authorities for the specific programs he/she is leading
  • Prepare meeting requests, briefing documents, coordinate and prepare teams for meetings, and interface with regulatory authorities
  • Coordinate and prepare responses to questions, requests for information from regulatory authorities
  • Monitor, analyze, and disseminate intelligence on regulatory matters that may affect ongoing development programs
  • Train and mentor other regulatory affairs personnel
  • Other activities as may be assigned

To apply please email resume and cover letter jobs@tseworldwide.com

VP; Pharmacovigilance

The VP Pharmacovigilance will build and lead the Pharmacovigilance group, provide hands-on medical monitoring, and strategic leadership for assigned investigational and marketed products. This individual will oversee the operational infrastructure required to oversee all aspects of adverse event collection, processing and reporting from clinical trials, post marketing and other sources, as applicable. This critical role provides strategic guidance to other functions (such as Data Management, Biometrics, Clinical Operations, Clinical Development) involved in adverse event collection and safety management throughout the lifecycle of therapies. The role will be based in the Bay Areaand will report directly to the Chief Medical Officer. 
Key Responsibilities

  • Leads and directs all aspects of pharmacovigilance activities for assigned investigational and marketed products 
  • Responsible for developing, executing and maintaining risk management strategy for assigned products 
  • Authors, reviews and provides input for drug-safety related regulatory reports and clinical study documents including periodic aggregate reports, case series analyses, regulatory submission documents 
  • Contributes to the development of internal processes including SOPs, Guidelines and Work Instructions 
  • Acts as medical and scientific subject matter expert for the pharmacovigilance capabilities build of a growing function within the Company 
  • Leads the labeling activities for the safety sections of the assigned product/indication 
  • Leads the creation of responses to safety questions from Regulatory Agencies for the assigned products/projects, and reviews and/or contributes to responses for safety questions for non-assigned products/projects 
  • Contributes to the Safety Medical Teams for meetings associated with assigned products/indications 
  • Designated Subject Matter Expert for medical questions related to processing ICSRs in partner audits and regulatory inspections 

Knowledge, Skills and Experience

  • MD (or equivalent) 
  • Minimum 15 years of experience in medical drug safety in the pharmaceutical industry and demonstrated results in managing the multiple facets of clinical safety and pharmacovigilance 
  • Substantial knowledge and experience with drug safety medical assessments in clinical trials and post market 
  • Experience in developing risk management strategies and writing risk management plans 
  • Experience and extensive working knowledge with Drug Safety Databases, data analysis tools, and document management systems 
  • Understanding of how global drug safety related regulations are applied 
  • Experience in leading cross functional drug safety team and cross-departmental interactions with clinical development, medical affairs, regulatory affairs, and commercial groups 
  • Excellent knowledge of drug development process 
  • Strong leadership and oral/written communication skills 
  • Ability to travel up to 20% of the time domestically and internationally 

Want to apply? Please send your resume to Michael Tal Sharon


Gene Therapy – Leadership Opportunities

TSE is pleased to announce a partnership with several early stage (pre-IPO) but well funded companies in the AAV Gene Therapy space in Boston and Cambridge, MA, NYC, Philadelphia and San Francisco

Open positions will be created and posted soon but will include:

  • CSO
  • S/VP Head of Translational Biology
  • CMO
  • Head of Clinical Development
  • Director, Clinical Operations and Program Management

We’re very excited to be able to collaborate with these companies working to advance potential life saving treatments across many Rare Diseases

Please stay tuned for updates here and on LinkedIn

Feel free to email me as well Email



A/D Strategic Planning – Bay Area

The Strategic Planning & Project Management Group’s (SPPM) primary objective is to achieve and maintain sustainable growth by maximizing value and prioritizing resources across the portfolio. The Associate Director, Strategic Planning will play a critical role in driving success by contributing to this objective. He/she will be integral to executing on algorithm and approach to balancing opportunity and risk across therapeutic areas, including building and assessing business cases (e.g., new indications, new geographies) within the portfolio. This person will be in a key position to “connect the dots” across groups, functions, and therapeutic areas to optimize strategic decisions and execution. He/she will interface often with the Senior Management Team and is expected to communicate in a clear and data-driven manner, from written communication to live presentations. This person will be based in Palo Alto and report to the VP, Strategic Planning & Project Management group.

Key Responsibilities

• Collaborate across functions to develop business cases (e.g., new indications, new molecules, new geographies) for new opportunities

o Evaluatebusinesscaseswithinportfoliocontexttoprioritizeandre-prioritizeopportunities across the company

o Ensure company resources (people, investment, time, energy) are aligned with prioritized opportunities

  • Collaborate with Groups within the Senior Management Team (e.g., Endocrinology Rare Disease Group) to strengthen cross-company view, decision-making processes, and communication; set agendas, as well as communicate decisions, action items, and minutes to Groups’ relevant stakeholders
  • Develop agendas and materials, and drive execution for key internal and external milestone meetings (e.g., board materials, Corporate Monthly Reports)
  • Monitor, analyze, and disseminate competitive intelligence (including press releases, SEC filings, company websites, conference communications)
  • Stay current on key publications (e.g., scientific literature, analyst reports, regulatory landscape changes) and share findings with key stakeholders
  • Engage with and support Project Directors in their efforts to drive projects’ strategic decisions, timelines, and budgets
  • Support business development efforts to bolster sustainable growth across therapeutic areas, including new technologies, licensing partners, geographic partners
  • Lead special projects
  • Lead/contribute to operational initiatives, as needed – examples could include:

o Scenario planning and forecasting use of drug supply
o Acting as point of contact for external partners (licensing partners) o Contributingtobrandnaming

• Establish processes, structures, and templates to support growth (e.g., business case templates, out-of-budget requests, subscriptions tracker)

Knowledge, Skills and Experience

  • Bachelor’s degree required, preferably in Life Sciences
  • MBA or advanced degree in Life Sciences (or related field) preferred
  • At least three years relevant experience
  •  Experience in biotech/pharma, i.e., pharmaceutical R&D drug development knowledge and familiarity with key biotech/pharma functions and processes, strongly preferred
  •  Excellent analytical skills and ability to provide strategic insight and problem solve, quantifying options, tradeoffs, budget, and resources needed – Top-tier consulting and/or investment banking background strongly preferred
  • Exceptional interpersonal skills (including cultural sensitivity) and communication skills (including presentations, written communications)
  • Strong leadership skills, including ability to lead colleagues across line organizations outside of reporting relationships
  • Driven by curiosity and strong interest in learning; willing to “dig into the science”; dedicated to becoming an expert on the therapeutic areas, technology, products, competitors, and related areas
  • High level of organizational skills and attention to detail
  • Role model of the company vision, mission, and values
  • Ability to travel up to 20% of the time domestically and internationally

For consideration, email resume and cover letter to jobs@tseworldwide.com

Recruiters -any location

We are looking for recruiters of any level to come work with us.

Please visit our careers page https://wp-k1hwq7y3c2.pairsite.com/category/careers/ to see the positions we typically support for our clients.

Send resume and cover letter to jobs@tseworldwide.com

CNS Research Scientist I / II

This position is part of our CNS gene therapy team and involves contributing experience and knowledge to the design and analysis of animal studies using AAV vectors. This includes the development of strategies to test these reagents both in vitro (e.g. primary human cells and iPSCs) and in vivo (mammalian model systems). The position further requires remote management of CROs, site visits, and hands-on analysis of study samples. The position also supports the development of techniques and processes for the successful translation of this technology into the clinic.

The position requires a capacity for constant innovation in pursuit of company goals, creativity, and adaptability. The environment is exciting, fast-paced, and offers the opportunity to work at the cutting edge of gene therapy for rare CNS diseases and small molecule development for cancer.


  • –  Management of CROs for CNS centric in vitro and in vivo studies
  • –  Protocol development for in vivo studies in disease models
  • –  In vitro testing of patient-derived iPSC and differentiated cells
  • –  In vitro testing of AAV lead designs
  • –  Oversight of small molecule lead compound validation in vitro and in vivo
  • –  Understanding and interpretation of patient-related data and its integration with experimental and therapeuticdesignRequirements:
  • –  Ph.D. in CNS biology or related field
  • –  Experience with CNS-targeted AAV gene therapy and the generation/use of AAV gene delivery vectors
  • –  Proficiency in brain physiology / pathology
  • –  Extensive experience with mammalian cell culture
  • –  Mastery of basic molecular biology and biochemistry
  • –  Strong communication and data presentation skills
  • –  Ability to work in a team-oriented, multidisciplinary environment

Chief Financial Officer -Boston/NY/San Francisco

Several of our Biotech client have reached out to discuss 2019 CFO hires.

For consideration or to set up time to discuss, please contact


Associate Director, Forecasting & Analytics

Bay Area, CA

Position Summary

The position will be based in Palo Alto and will report directly to the Vice President, Commercial Analytics.

The Associate Director, Forecasting & Analytics will be responsible for design, development, oversight and delivery of global forecasting process/initiatives, for the portfolio. This person will be an integral partner to the business operations (Finance and Supply Chain), as well as the commercial teams (Marketing,Market Access, Market Research, Sales and Operations).

Key Responsibilities
In close collaboration with Finance, deliver complete, accurate, validated, and timely forecasts
Develop and maintain a robust commercial forecasting capability to
ensure internal and external alignment on business expectations
Operationalize forecasting governance and processes and then leading
the execution of these
Develop revenue and supply/demand forecasts in support of financial
planning processes, i.e., Operating Reviews and budgeting processes
Contribute to annual, short-term, and long-range planning forecasts
Manage all aspects of new launch, inline and portfolio forecasts includingdeveloping and maintainingepidemiology and prescription-based modelsLead the development of evidence-based forecast scenarios in driving
strategic decisions.
Carry out base-case and scenario analyses (TPP’s, launch year, market share, price, sales ramp, etc.) to support decision making by key partners
and stakeholders including Commercial, Business Development/Strategy, Finance, Manufacturing, and executive leadership, BOD, etc.
Conduct and incorporate ad hoc analyses of forecast sensitivity which
may involve estimates of monthly demand for in-line products using
weekly data and/or risk and opportunity sizing
Collaborate across functions to ensure inputs and assumptions are captured and documented in forecasts,
drives alignment on financial projections, and secures approval from
senior and executive leadership
Incorporate the results of primary research into the forecast model(s) to
reflect anticipated risks andopportunities
Use patient flow forecast models, patient based forecast models, and statistical trending and ensure alignment on forecast assumptions and other
critical analytical assessments with business partners
Ensure that forecasts address the impact of market dynamics and critical events, are logically designed andwell documented
  • Implement quality control processes into the forecast process
  • Identify key business issues that impact short-term and long-range product and market forecasts; clearlyand pro-actively surface these issues
  • Lead national-level performance reporting and diagnostics including reconciliation with forecasts; will ownnational analytics data sets; will partner with Market Research counterpart on key business analysis (proactive and reactive), in responding to key business questions and in commercial reporting and launch tracking/monitoring
  • Present findings and make recommendations to management regarding: brand, market growth, inventory dynamics, patient incidence, prevalence, diagnosis, treatment trends, competition and payer environment
  • Demonstrated excellence in consensus building, characterizing and communicating uncertainty, and be able to explain issues from aggregate trends to modeling mechanics
  • Participate in ad-hoc projects by working collaboratively across product teams and other functional

• Stay abreast of novel forecasting and analytical methodologies and processes

Knowledge, Skills, and Experience

  • Bachelor’s Degree required; Master’s Degree or MBA preferred
  • Minimum of 8 years of forecasting and modeling experience
  • Experience in Specialty or Rare Disease, preferred
  • Superior analytical skills with proficiency in a broad range of data analysis and intelligence generation
  • Significant expertise in analytics, forecasting, modeling methodologies and a solid understanding ofcompetitive intelligence and market research
  • Ability to run statistical analyses, contribute to new analysis methodologies, and engage withanalytics/statistical modeling experts
  • Advanced knowledge of MS Office (Excel, PowerPoint, Word) and strong ability to present quantitativedata in graphical form is required
  • Strong team player with ability to manage conflicting priorities
  • Demonstrated ability to work with many cross-functional partners
  • Ability to understand and influence decisions
  • Ability to interact and communicate with all levels in the organization
  • Self-starter. Proactive in nature, actively participates and self-motivated
  • Excellent project management skills with demonstrated ability to lead multiple projects and priorities
  • Demonstrated ability to work effectively in cross-functional teams is required with a history of leadership,initiative in achieving organizational objectives
  • Strong communication/influencing skills and executive presence required
  • Ability to travel up to 10% of the time domestically and internationally

Gene Therapy News

After a recruiting journey with candidates from Europe, Asia and all over the US, I am happy to announce that our client Grace Science, LLC has selected a Bay Area local to lead their ambitious R&D effort in Gene Editing/Gene Therapy, Rare Diseases, Neuromuscular and Oncology. It has been a privilege to work with the team and I am certain great things are to come.

For more information about Grace Science and their technology please visit

VP, Marketing

VP, Marketing, Bay Area

Position Description & General Requirements

Reporting to the Chief Commercial Officer and based in Palo Alto, the Vice President of Marketing will provide the leadership, vision and functional expertise for developing a comprehensive pre-commercialization launch and execution plan for TransCon Growth Hormone, PTH and other pipeline compounds. 

  • Develop the strategic, tactical and execution launch plan for TransCon Growth Hormone and execute plan seamlessly to meet or exceed launch plan objectives.
  • Role model of the company vision, mission and values (patients, science, passion).
  • Hires and develops best in class talent aligned with our company vision, mission and values. 
  • Develops and sustains highly collaborative and effective cross-functional working relationships with US and European colleagues.  
  • Develop key external relationships with key opinion leaders, vendors, consultants, agencies and business partners. 
  • Demonstrates high level of professional expertise within the functional discipline.
  • Turns strategy into action; proactively develops own functional area to prepare for the future to ensure long-term success, including brand life-cycle management. 

Position Specific Requirements

  • Successful track record developing pre-commercialization launch planning and building at least two significant pharmaceutical brands and at least one in the rare disease space. 
  • Successful working in both big pharma as well as small biotech start-up company environments. 
  • Entrepreneurial leader who builds strong teams of people with diverse experiences, perspectives and talents and creates an environment in which the team is highly motivated and engaged to work together to deliver exceptional results consistent with company vision, mission and values.
  • Proven ability to develop clear, differentiated and compelling brand positioning, with corresponding brand core messaging and crystallized product promise.
  • Possesses broad base of industry experiences including working with specialty pharmacy,     advocacy, payers and PBMs and incorporating HEOR into overall marketing plan and brand value proposition.
  • Science-based leader with strong analytic skills and proficient in developing accurate brand forecasts.
  • Exceptional planning & organizational skills and attention to detail including budget management.  
  • Demonstrated track record of creating an aligned partnership and seamless execution with sales leadership.
  • Experience developing high impact marketing and collateral materials
  • Experienced in building metrics to measure impact of marketing efforts
  • Experienced in developing local market strategies and marketing initiatives to maximize business opportunities in diverse markets 
  • Possesses strong and broad industry relationships and network with agencies and vendors who is skilled in successfully negotiating contracts.


  • Minimum of 12 years of progressive experience in the biopharmaceutical industry in Marketing, Market Access, Sales, or Business Development, in both small and large companies, including supervisory experience.
  • Minimum of 10 years of Pharmaceutical Marketing.
  • Bachelor’s degree required, MBA or graduate level degree preferred. 

Other Valuable Capabilities

  • Experience in endocrinology and the growth hormone market
  • Experience with drug-device combination products 
  • Experience with digital advertising, including DTC  
  • Experience with public relations and advocacy 
  • Experience pricing new pharmaceutical, globally
  • Global marketing experience  

Responsibilities & Main tasks

  • Ability to travel up to 25% domestically and internationally 

Vice President, Medical Affairs

Vice President, Medical Affairs, Palo Alto, CA

Vice President, Medical Affairs who will lead the development of the Company’s medical strategy for commercial products and work closely with other Departments including Commercial leading the development of the Company’s medical affairs strategy for all to be marketed products. S(he) will be responsible for designing and implementing medical strategies and tactical plans while providing thought leadership and tactical execution for medical publication planning, medical education, medical information system development, field medical liaisons and medical communication. S(he) will also work closely with the safety and pharmacovigilance professionals and strategic alliance partners.

With the Chief Medical Officer and Chief Commercial Officer, the VP, Medical Affairs defines strategy and will develop and refine Medical Affairs policies and procedures and SOPs, to ensure and maintain excellence in standards and practices. The VP, Medical affairs will provide significant support for phase 2/3 recruiting activities across all products, lead the company’s KOL advisory board management, and run the investigator-initiated trials program. Additionally, the VP, Medical Affairs will design and execute on phase IV studies and, when appropriate, lead the phase IV clinical program. This position will report to the Chief Medical Officer, Clinical & Regulatory.

Specific Responsibilities

  • Develop and implement the US and global medical affairs plan across products
  • Develop and refine Medical Affairs policies and procedures and SOPs
  • Work closely with commercial and clinical development/regulatory in designing and implementing launch strategies and tactics, and life cycle planning
  • Provide assessments of product opportunities and threats
  • Develop strategic imperatives and tactical plans to enhance healthcare practitioner education to improve patient outcomes
  • Provide leadership to the Medical Affairs team and actively lead the design and conduct of Phase IIIB/IV trials and medical materials review.
  • Provide medical expertise in development of promotional materials.
  • Develop strategy for review and approval of investigator-initiated studies
  • Develop strategy for review and approval of CME programs
  • Conceive, structure, and conduct of US advisory boards and steering committees
  • Foster research relationships with key research centers in the US
  • Interact regularly with key medical opinion leaders
  • Work with commercial colleagues to develop and implement the company’s publication strategy
  • Collaborate with Commercial, Legal, and Regulatory for development and review of labeling, advertising and promotional materials
  • Monitor the competitive environment to sustain expertise in therapeutic area treatment management and new therapies, competitive products and features
  • Contribute to coaching and training Medical Science Liaisons and related sales force personnel on company clinical, medical, and scientific matters

Position Requirements & Experience

  • MD degree, with specialization in endocrinology preferred, and pediatric endocrinology highly desirable.
  • Experience with hGH treatment in pediatric GHD preferred.
  • Experience designing and executing clinical trials
  • Experience with GHD clinical trials a plus.
  • Excellent understanding of the drug development process and GCPs.
  • Strong clinical/scientific background/aptitude.
  • Prior experience in meeting the high standards required for drug development within a regulated environment consistently.
  • Previous pharmaceuticals industry experience in a Medical Affairs leadership role
  • Previous launch experience would be ideal with past success working in highly matrixed, cross-functional environment requiring excellent cross functional collaboration to achieve successful results

Personal Characteristics & Cultural Fit

  • Strong writing and presentation skills.
  • Team player and highly collaborative with executive team, colleagues, investigators, and clinical research partners.
  • Ability to follow complex direction/processes under pressure.
  • Proficient balancing multiple routine tasks simultaneously to achieve goals.
  • Very strong organizational skills, with attention to detail.
  • Works well under general direction, with ability to independently determine and develop approaches to non-routine problems – a self-starter.

Bay Area VP Positions Filled- Rare Diseases

I am thrilled to announce that after fewer than 5 weeks, we have had two VP roles have offers accepted for a rare disease client in the San Francisco Bay Area.

This was a national search bringing VP level talent from powerhouse commercial pharmaceutical companies to a company preparing to launch multiple assets.

To view the full positions:

VP, Market Access

VP, Commercial Analytics

To find out more about helping your company with open positions, contact me at jobs@tseworldwide.com

To see if an open opportunity is right for you, please visit out Careers page


Vice President /Head of Information Technology – Filled

The Vice President, Global Information Technology (IT) is responsible for setting the enterprise IT strategy and driving cross-functional IT needs by being well versed with industry trends and emerging technologies.  He/she must be continuously be on the lookout for transforming the business through technology.  He/she will be responsible for overseeing a group of technology professionals accountable for global IT infrastructure and support.  He/she must also bring strong leadership to the team and create an environment that promotes professional development and growth.  The ideal candidate will balance the technical aspects of this position and the ability to integrate the company’s corporate strategy with IT priorities.  He/she must also possess excellent communication skills to provide clear and business focused (non-technical) communications to senior management.


  • Serves as the overall IT Lead, responsible for IT strategy, vision, reference architectures, governance, technology due diligence and selection, project delivery and management.
  • Serves as the chair of the Global IT Steering Team.
  • People management
  • Oversee a global team of 5-8 direct reports.
  • Set team’s annual deliverables/objectives, performance goals, and empower them to deliver our strategic priorities and objectives.
  • Select, develop and motivate a high talent team; mentor key technical resources.
  • Promote teamwork and leadership behaviors within own group, other peer groups, and across the organization.
  • Strategic Planning
  • Owns the development of our target state architectures and five year roadmaps, working closely with the business and solution delivery teams (internal and external) to align and integrate their respective strategies.
  • Plans, sets, and documents strategic architecture vision and tactical directions for existing and forthcoming products.
  • Evaluates and determines the balance between in sourced vs. outsourced models for IT services.

Enterprise Architecture

  • Owns and operates the Organization System Selection/Implementation process, evaluating all significant application, data, infrastructure and services projects and production systems.
  • Drives technology selection process and manages/controls the software and hardware technology stack.
  • Owns technology standards assessment and adoption for IT technologies.
  • Sets the overall guidelines, standards and architectural principles for architecting solutions across the portfolio; manages the governance of these standards at the program and project level.
  • Establishes enterprise data architecture strategy and manages enterprise-wide storage, backup, integration, and accessibility of data.
  • Establishes strong working relationships with senior business, operations and technology management, in the capacity of a trusted advisor on IT matters.
  • Engages the business and process owners and leads the collaborative planning effort to leverage emerging technologies for addressing strategic enterprise goals.
  • Communicates the practical implications of system selection and implementation, architectural decisions, issues and plans to senior business, systems delivery, and infrastructure management.
  • Identifies and promotes opportunities for cross-business sharing / re-use of application components, rationalization of application portfolios and integrated architectures.
  • • Establishes data management strategy and policies in conjunction with various functional teams
Project Management
  • Establish Project Management capabilities to apply rigor to portfolio analysis (including sequencing of projects), budgeting & planning, tracking and resolving issues, risks and dependencies across projects and programs, coordinating executive communications/status reporting and coordinating resource management and staffing needs.


  • Master’s degree or MBA with a degree, or concentration in, Computer Science, Information Technology or related discipline and a minimum of 15 years progressively responsible experience at least 8 of which were spent in a management role.
  • Experience in a pharmaceutical or biotechnology or related environment is preferred.
  • Global experience in a pharmaceutical, biotechnology or related environment ideally including leadership experience of an IT function during the expansion of commercial business globally.
  • Demonstrated ability to effectively collaborate and communicate with a variety of audiences and stakeholders including, but not limited to, Executive and Senior Management, Business Leaders/Managers and colleagues worldwide.
  • An active listener with the demonstrated ability to proactively and confidently engage with global key stakeholders to gain an understanding of the business’ evolving IT needs, develop and recommend innovative and cost-effective solutions and explain technology-related issues to non-technical audiences.
  • Demonstrated experience developing, leading and supporting an IT vision and direction including demonstrated experience developing long- and short-term strategic IT plans, developing the associated financial analyses and translating budgeted plans into tactical, actionable operational initiatives.
  • Demonstrated, hands-on experience as a project manager with strong planning skills, the ability to set and manage expectations and deliver on projects within the committed timeframe and budget.
  • Demonstrated ability to analyze problems and resolve conflicts.
  • Demonstrated ability to embrace, adapt to and actively manage change, including experience facilitating the transition from traditional client/server systems to cloud-based solutions.
  • Hands-on experience negotiating and managing vendor contracts.
  • Exceptional customer service orientation.
  • Demonstrated leadership ability and experience managing, coaching and mentoring direct reports.
  • Ability to influence without direct authority.
  • 20% domestic and international travel

To apply email your resume to jobs@tseworldwide.com

Head of Translational Development

The candidate will be responsible for both therapeutic areas: Oncology & Immunology. As the functional head of Translational Development , they will be at the interface with the Discovery and Development teams, with the aim of providing the successful implementation of stratification strategies, clinical biomarker and pharmacodynamic assays in the early clinical development phases.

Technical Skills:

   • Collaborations that impact all of research, or even across multiple functions.
   • Scientific and technical expert.
   • Proven track record of success in drug discovery and development.


   • Cell panel screening: define resistance mechanisms, sensitivity elements, PD markers and potential biomarkers of response
   • Genomics analysis from human clinical samples, cell screen samples and clinical trial support (defined clinical experiments from the development teams). This includes development of a high dimensional bioinformatics.
   • Clinical PD or Biomarker assays, translated from discovery (if applicable or appropriate) or developed specifically for early clinical use, assessing feasibility and applicability for companion diagnostics
   • Application of model systems (in collaboration with the disease biology and in vivo pharmacology groups) beyond those routinely employed by discovery teams that aid in patient stratification/response and compound use, either        in-house or as a collaboration
   • Translational Development representation to the Development Project teams
   • Participate in formulating disease area strategy for target selection and validation
   • Evaluating, in conjunction with BD and the established teams, the potential in-licensing opportunities that may include potential therapeutics, emerging technologies, processes or capabilities that will enhance our Drug Discovery and Early Development efforts.
   • Being part of the team responsible for establishing key alliances with academic centers, co-operative groups and government agencies for cost effective implementation of  R & D and early development strategy


   • Track record in large and small companies, leading innovative efforts to deploy technologies and assays for enhanced translational capabilities
   • Excellent communication, managerial and scientific qualities are expected
   • Ability to interact effectively across boundaries using influencing and relationship building skills.
   • Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals.

Other Attributes:

   • A problem solver who creatively and knowledgeably transcends departmental function to act as a resource to entire research effort and senior managers in development.
   • Identifies issues early and proposes innovative solutions.
   • Communicates within the larger organization and external community.
   • Provides expert guidance to multi-disciplinary teams and senior management.
   • A leader whose scope of influence stretches across.
   • A leader who influences external scientific community.

Requirements & Education:

   • MD, DO or PhD
   • 10 years industry experience

VP, Market Access (Offer Accepted)

Reporting to the Chief Commercial Officer and based in Palo Alto, the Vice President of Market Access will provide the leadership, vision and functional expertise for developing a comprehensive pre-commercialization market access launch and execution plan for Growth Hormone, PTH and other pipeline compounds.

  •   Develop the market access strategic, tactical and execution launch plan for Growth Hormone and execute plan seamlessly to meet or exceed launch plan objectives.
  •   Role model of the company vision, mission and values (patients, science, passion).
  •   Hires and develops best in class talent aligned with our company vision, mission and values.
  •   Develops and sustains highly collaborative and effective cross-functional working relationships with US and European colleagues.
  •   Develop key external relationships with payers, KOLs and business partners.
  •   Demonstrates high level of professional expertise within the functional discipline.
  •   Turns strategy into action; proactively develops own functional area to be prepared for thefuture to ensure long-term success, including brand life-cycle management.Position specific requirements
  •   Successful track record developing pre-commercialization market access launch planning strategies for at least two significant pharmaceutical brands and at least one in the rare disease space.
  •   Successful working in both big pharma as well as small biotech start-up company environments.
  •   Entrepreneurial leader who builds strong teams of people with diverse experiences, perspectives and talents and creates an environment in which the team is highly motivated and engaged to work together to deliver exceptional results consistent with company vision, mission and values.
  •   Possesses broad base and in-depth understanding of reimbursement issues, payer segments, use of specialty pharmacies, the J-Code application process, managed market customers including private and public payers, national and regional health plans, stateMedicaid, Medicare Part B and D, VA/DOD, PBM’s, Employers, IDNs, Medical Groups and ACOs.
  •   Extensive relationships and contracting experience with payers, health systems and organized customers at the national and regional level.
  •   Proficient developing distribution strategies for a diverse product portfolio.
  •   Proficient managing government chargeback process.
  •   Proficient building and managing a HUB service.
  •   Experience working with HEOR and developing successful outcome based contractingstrategies in crowded mature markets and maximizing GTN.
  •   Demonstrated ability to develop an insightful, differentiated and impactful market accessbrand value proposition, which uniquely resonates with the payer and organized customerresulting in above expected market penetration rates.
  •   Science-based leader with strong analytic skills.
  •   Exceptional planning & organizational skills and attention to detail including budgetmanagement.
  •   Possesses strong and broad industry relationships and professional network of influentialmarket access leaders, consultants, agencies and vendors to be in-synch with industry best practices and competitive strategies as well as on the cutting edge of future innovative changes to the payer and industry landscape.Qualifications
  •   Minimum of 12 years of progressive experience in the biopharmaceutical market, in both small and large companies (or related experience in management/strategy consulting and or equity research focused on the biotech and/or pharmaceutical sector), including supervisory experience.
  •   Minimum of 8 years of progressive experience in pharmaceutical market access.
  •   Bachelor’s degree required, MBA or graduate level degree preferred.
  •   Other valuable capabilities
  •   Experience in endocrinology and the growth hormone market
  •   Experience with drug-device combination products
  •   Experience pricing new pharmaceutical, globallyResponsibilities & Main tasks

 Ability to travel up to 25% domestically and internationally …

To apply, please email resume to jobs@tseworldwide.com

VP Commercial Analytics (Offer Accepted)

VP Commercial Analytics; Palo Alto, CA

Reporting to the Chief Commercial Officer and based in Palo Alto, the Vice President of Commercial Analytics will provide the leadership, vision and functional expertise for developing a comprehensive pre-commercialization market research strategy and analytics support plan for the successful launch and execution of Growth Hormone, PTH and other pipeline compounds.

  •   Develop the commercial analytics strategic, tactical and execution launch plan for Growth Hormone and execute plan seamlessly to meet or exceed launch plan objectives.
  •   Role model of the company vision, mission and values (patients, science, passion).
  •   Hires and develops best in class talent aligned with our company vision, mission and values.
  •   Develops and sustains highly collaborative and effective cross-functional working relationships with US and European colleagues.
  •   Develops key external relationships with consultants, vendors and business partners.
  •   Demonstrates high level of professional expertise within the functional discipline.
  •   Turns strategy into action; proactively develops own functional area to prepare for thefuture to ensure long-term success, including brand life-cycle management.Position specific requirements
  •   Successful track-record of leading or senior member of the commercial analytics function proficient in developing, leading and executing the commercial analytics function for a diverse array of therapeutic areas.
  •   Successfully launched at least one pharmaceutical brand, ideally two or more, and at least one rare disease drug.
  •   Successful working in both big pharma as well as small biotech start-up company environments.
  •   Entrepreneurial leader who builds strong teams of people with diverse experiences, perspectives and talents and creates an environment in which the team is highly motivated and engaged to work together to deliver exceptional results consistent with company vision, mission and values.
  •   Expert in qualitative and quantitative market research, analysis and brand forecasting.
      Proficient in designing, conducting and interpreting primary and secondary data analysis.
  •   Develop and analyze a wide range of data, extracting critical findings and providing insightsto aid in sound decision-making.
  •   Proficient developing all functions related to third party data acquisitions, master datamanagement, data warehousing, lead the collection and distribution of relevant data fromthe data aggregator, data compliance and integrity.
  •   Develop field alignment, call plan, field sales reports, and incentive compensation plans,KPIs, dashboards, measuring and assessing field force effectiveness and developing CRMsystems.
  •   Successfully negotiate vendor contracts.
  •   Develop presentations for senior leadership and other stakeholders.
  •   In-depth experience with specialty pharmaceuticals, specialty pharmacy, HUB services and payer contracting.
  •   Evaluate business development opportunities, conduct market analysis, product assessments, due-diligence, and forecast modelling.
  •   Possess relationships with broad base of vendors necessary to lead this function.
  •   Exceptional planning & organizational skills and attention to detail including budgetmanagement.Qualifications
  •   Minimum of 12 years of progressive experience in the biopharmaceutical market, in both small and large companies (or related experience in management/strategy consulting and or equity research focused on the biotech and/or pharmaceutical sector), including supervisory experience.
  •   Minimum of 10 years of commercial analytics experience.
  •   Bachelor’s degree required, MBA or graduate level degree preferred.
  •   Other valuable capabilities
  •   Global experience including product launches, building global master data management anddata warehousing function and working with international colleagues.
  •   Experience evaluating effectiveness of marketing tactics including digital advertising andDTC advertising.
  •   Experience pricing new pharmaceuticals, globally.
  •   Experience in endocrinology and the growth hormone market.
  •   Experience with drug-device combination products.

to apply, please email resume to jobs@tseworldwide.com


Chief Scientific Officer – Rare Disease Platform

We have a a a unique opportunity to join a well-funded startup looking at new platforms and technologies to treat rare and unmet neurodegenerative and neurological diseases – particularly in pediatric patients.

Academic advisory board consists of well-known industry giants and Nobel recipients.


For more insight, please contact tsharon@tseworldwide.com




Director, Pipeline Commercialization Strategy

Summary Description

Position will lead commercial strategy and drive the execution for pipeline programs. This position works closely with senior leaders across multiple functions, including members of the program core team and commercial leaders.

This position drives commercial planning and market preparation activities by providing objective, in-depth information on current and future markets, customers and competitors. The position identifies critical business issues and opportunities for growth, collaborates with commercial/cross-functional teams, and drives strategies to set the direction for the product.


  • Lead global commercial strategies for programs in Rare Diseases
    • Provide evaluation of market opportunities, develop business / go-to-market plan, secures resources and lead appropriate market development/ pre-launch activities.
  • Liaise with other core team members to support team activities and strategy development. Play an integral role in guiding program strategy.
  • Provides expert guidance and leadership on the commercial potential and market landscape to core teams, informing strategies such as medical plans and life cycle plans
  • Partner closely with medical affairs and patient advocacy to ensure physician and patient needs are addressed for innovative, paradigm-shifting therapy
  • With market access colleagues, ensure access and reimbursement strategies are in place to support patient and physician demand
  • Oversee the development of market research plans, competitive landscape assessment and revenue forecasts.
  • As needed, support business development efforts by serving as a direct commercial interface and providing evaluation of market opportunities


  • 6+ years in biotech / pharmaceutical marketing role
  • 10+ years in biotech / pharmaceutical industry
  • Experience leading marketing efforts
  • Experience working in core team setting and managing team
  • Excellent communication, collaboration, strategic and analytical skills are required

Preferred qualifications:

  • Product launch and pre-launch experience
  • U.S. and international experience


  • Bachelors, preferably in life sciences or economics
  • MBA, strongly preferred

Engagement Manager – Life Sciences Strategy

Engagement Manager – Life Sciences Strategy

Heading Engagement Manager – Life Sciences Strategy

San Francisco, Boston or NYC

Engagement Managers are responsible for leading workstreams and engagements, translating client needs into project tasks and deliverables. Engagement Managers manage day-to-day problem-solving and team analytical activities, and serve as key liaisons between consulting team members, VPs and Partners, and our clients. Senior Consultants are also responsible for mentoring and developing team staff. Our teams work on a variety of client issues. The range of assignments includes developing long-term strategies for organizations, evaluating the potential acquisition of businesses, improving educational achievement outcomes, developing new marketing channel strategies, reducing operating costs, and evaluating new business ventures. Responsibilities: Develop business strategies using tools such as market analysis, customer research, macroeconomic forecasting, and portfolio optimization. Review transaction rationale and/or deal documents to identify critical business issues and risks relating to a proposed transaction. Assist in defining the objective and scope of strategy engagements and client deliverables in consultation with the Vice President and Managing Director Manage workstreams/projects from initial data collection and analysis to creating final client deliverables Effectively manage and motivate workstreams and teams with diverse skills and backgrounds Develop and maintain relationships with clients Develop, manage and mentor junior team members at the Associate, Senior Associate, and Consultant levels. Qualifications: Preferably, an MBA with two years of related work experience or graduate degree with at least three years of related work experience, with a particular focus on client advisory or strategic planning within a professional services environment. At a minimum, a bachelor’s degree in a life sciences discipline with outstanding academic performance and at least 5 years of related work experience. Experience managing business strategy and M&A strategic diligence projects in life sciences in complex environments. Ability to make detailed assessments of industry, products, markets, competitors and customers to identify risks and opportunities in pharmaceuticals, diagnostics, device or life sciences tools. Commitment to staying at the cutting edge of knowledge in the life sciences industry. Strong aptitude for quantitative and qualitative analysis and the ability to link business strategy to performance. Excellent problem solving, project management, facilitation and interpersonal skills. Proficient in the English language, including the ability to listen, understand, read and communicate effectively, both in writing and verbally, in a professional environment. Effective organization and time management skills with ability to work under pressure and adhere to project deadlines. Able to multitask and work efficiently in a fast-paced environment. A strong work initiative, high energy level and the ability to adapt to new challenges and ideas. Willingness and ability to travel, when necessary (approximately 25-50%).



Head of Clinical Development – Immunotherapy and Biomarkers

Head of Clinical Development – Immunotherapy and Biomarkers


  • Provide clinical leadership and focus for R&D to ensure the creation of comprehensive product development plans from concept to launch
  • Develop actionable plans with anticipate regulatory requirements and timelines to support validation and labeling efforts
  • Provide timely product development requirements to operations which will support scaling infrastructure and capacity to support new product/market needs.
  • Experience writing and implementing research protocols, reviewing and interpreting data, preparation of study reports, data analysis and presentation of data to internal and external audiences.
  • Ability to work in a matrix environment with other departments to include Project Management, Regulatory Affairs and Medical Affairs.
  • Excellent oral, written and personal communication skills.
  • Strong clinical research, leadership and management experience
  • Demonstrated experience leading collaborations with RA, QA, R&D, Medical and Commercial to successful product launch.

please email CV to jobs@tseworldwide.com

Vice President Corporate Strategy : NJ-NYC-San Francisco

Multiple opportunities to use your consulting experience client side in  high-intensity, high-impact experience similar in structure to top-tier consulting firms (McKinsey, Bain, BCG…).  You will be mentored and supported by the team’s leadership which has extensive consulting and industry expertise.

Industries include: Pharma, Biotech, Financial Services, Insurance, Tech and Telecom


  • Oversee project structure, approach and process
  • Manage overall project delivery in terms of quality and respect of deadlines
  • Lead and manage presentations for management
  • Bring content expertise and drive resolution of complex issues
  • Build long term relationships with clients
  • Lead proposals to acquire new projects
  • Manage and motivate resources at all levels


  • Senior level Project Manager/Consultant  with executive presence and comfort working with senior executives
  • 7+ years of experience leading large transversal projects
  • MBA Preferred


Problem Solving

  • Manages one or two projects independently
  • Designs and structures the overall support
  • Supervises work schedules to ensure project delivery


  • Presents convincingly in client interactions
  • Writes sharp and straight-to-the-point management summaries

Quality of work:

  • Ability to deliver quality results against fast paced project deliverable deadlines
  • Sets high quality standards
  • Provides overall project presentations in high quality
  • Proven ability to execute complex projects with large number of dependencies

Client Relationship:

  • Builds legitimacy with clients while preserving independence


  • Is seen as a role model to the entire team


  • Solves client conflicts at management level
  • Provides honest and independent advice

Qualified candidates should email resume to jobs@tseworldwide.com



Director, Market Access Strategy

Director Market Access Strategy  – Bay Area, CA

The Market Access Strategy, will lead US value, access and reimbursement strategy development for gene therapy program. This position works closely with multiple stakeholders within the commercial, medical affairs, and key corporate functions. This position reports to the Senior Director, Market Access Strategy and Payer Policy within North America Commercial Operations. This newly created position drives strategies to ensure market access success by objectively evaluating the US coverage and reimbursement environment and providing subject matter expertise to influence commercial planning and market entry plans. The position identifies access issues and opportunities, and collaborates with commercial/cross-functional teams that address them. Responsibilities: • Lead development and ensure implementation of US market access strategies for  program • Evaluate opportunities that can be translated into strategies and actions to prepare innovative gene therapy for market access success • Collaborate with commercial market access and commercial operations functional leads responsible for implementation strategies • Project team lead the development of global market access value proposition, global value dossier, evangelize on key publication opportunities that ensure access and team access deliverables. • Lead US market access horizon scanning and trend assessment for gene therapies that provide insights and key considerations • Actively serve as US market access SME/voice for gene therapy in the commercial organization • Partner with US pricing and policy functions to evaluate and establish pricing, coverage, and reimbursement environment that supports provider & patient demands for gene therapy Required Experience/Skills: • 8+ years US pharmaceutical industry experience with increasing responsibilities • 5+ years of experience in developing and implementing innovative US market access and reimbursement strategies in a corporate role • Deep understanding of health policy & health system environment for transformative and rare therapies • Superior problem-solving skills, including demonstrated capability of applying previous experience to complex policy issues • Excellent communication, collaboration, influence, strategic and analytical skills are required • Highly organized and skilled at managing teams and vendor projects Preferred Qualifications: • US Product launch and pre-launch leadership • Rare Disease experience highly preferred Education: • Bachelors, preferably in life sciences or economics • MBA or MPH, preferred

to apply please email resume to jobs@tseworldwide.com

Genomics / Diagnostics Careers

Our genomics clients are growing rapidly and we are looking for the following:


  • Director – VP level candidates – Pharma Partnering; Nationally and possible EU
  • Site Head- San Francisco Bay Area and additional locations
  • VP, Translational Development – Oncology and Immunology – location open (multiple)
  • VP Clinical Development – Oncology and Immunology – location open (multiple)

For details and consideration, please send a note to tsharon@tseworldwide.com



New Opportunities and Successful Placements

Here’s a sample of our recent activity: ***Updated October-10-2019***

Open positions:

  • VP or SVP of Clinical Development- Boston Biotech 
  • COO or CBO San Francisco Biotech
  • CSO San Francisco Biotech
  • Senior Scientist-Director; DMPK
  • Director of Operations, NYC Healthcare
  • Sr/Director, IP Attorney – Boston Biotech
  • Exec Director, Late Stage Medical Lead – Rare Disease
  • Director, Field Medical Affairs – NJ
  • SVP, Head of Companion Diagnostics
  • Director, Business Development and Alliances (Field Based)
  • Head of Healthcare Product Development, San Francisco
  • VP, Cell Therapy Development, San Francisco
  • Head of Regulatory – Diagnostics
  • Boston Biotech Leadership opps – CFO, COO and CBO 
  • VP, CMC Gene Therapy – NJ
  • Director, S&E – Boston Area Biotech
  • CFO Boston Biotech
  • Director, Program Management – NJ Gene Therapy 
  • Director/AD Program Management – NJ
  • Director, Clinical Development – NYC
  • Director – Clin Ops NYC
  • Investment VP and Associate – Life Sciences Real Estate Incubator LA/NYC/Boston
  • Head of Gene Therapy Regulatory NY, NJ and Philadelphia
  • COO- Boston Biotech
  • Head of Discovery, Rare Diseases, Gene Therapy
  • COO-Boston Biotech
  • CFO-NYC Biotech
  • Director, Clinical Ops, NYC
  • VP, Marketing – Pre Launch- Bay Area (FILLED)
  • VP, Market Access – Bay Area
  • VP, Commercial Analytics – Bay Area
  • VP, IT- NJ
  • VP, Banking – NYC
  • Director, Worldwide Strategic Analytics; Oncology – NJ
  • Director of BD&L and Corporate Strategy – NJ
    • Director, Business Development & Clinical Collaborations Oncology Commercialization
    • Director of Market Insights and Business Intelligence, Boston
    • A/D, Forecasting and Market Analytics-Boston
    • Manager, Healthcare Predictive Analytics
    • San Francisco -A/D of Commercial Operation, Boston
    • VP, Operations Consulting – NYC Bank -SVP, Corporate Strategy and BD
    • Sr Director, Immuno-Oncology Portfolio -Director of Commercial Strategy, Rare Diseases
    • VP, Global Medical Affairs, Rare Diseases
    • Several Strategy Consultants
    • Global Lead, Search and Evaluation
    • Lead, Global Launch / Marketing
    • Clinical Research Physician, Oncology
  • Investment Banking Associate, Healthcare M&A

Principal or Senior Scientist, Vector Design AAV

Principal or Senior Scientist, Vector Design AAV – Bay Area


This is a position for a highly innovative, passionate, and energetic Scientist to develop adeno-associated viral vector technologies in an industry setting. The candidate should be extremely motivated to drive drug development. The Principal or Senior Scientist is part of a multidisciplinary research team responsible for using BioMarin’s Proprietary technology platform to develop gene therapy applications. 

Responsibilities include: 

  • Identification and development of new AAV Applications
  • AAV Capsids development
  • Vector design
  • Optimize Vector Cassette
  • Assist in management of projects with partners and/or contract laboratories


  • Preferably 7+ years of experience working as a scientist in an academic, research, laboratory setting or biotech/pharma company
  • This person must have extensive experience engineering AAV vectors
  • Exceptional publication record in leading peer reviewed journals
  • Experience interpreting and presenting data to internal and external stakeholders, and at national and international meetings
  • Strong critical, scientific, and strategic thinking skills; Strong problem solving and decision making abilities
  • Strong communication (verbal and written) skills
  • Experience and ability to work collaboratively in cross-functional teams
  • Drug development and/or extensive research training


  • A Ph.D. in the Biomedical Sciences.
  • Strong consideration given to Molecular Biologists

Email resume or CV to jobs@tseworldwide.com


Head of Clinical Development – Immunotherapy and Biomarkers



    The Vice President of Clinical Development will be responsible for establishing product requirements and development strategies for  Diagnostic Business Unit, while managing the execution of development plans for new and current products.  This important lead role will develop, plan and implement clinical research programs and trials. Lead the team to establish relevant product specification, evidence to support regulatory and payer requirements while addressing unmet clinical needs. The successful candidate will also present technology to key customers including clinical researchers, health care providers, and payers to gain engagement and support.  

    Vice President of Clinical Development will manage the allocation of personnel and financial resources to ensure the successful and timely completion of clinical product development goals.  This pivotal role will coordinate clinical product development with software development to effectively position clinical portfolio for long term success.  This hands-on leader will provide scientific expertise across the organization and drive cross-functional collaboration across all internal stakeholders while working closely with Medical Affairs. 


    • Provide clinical leadership and focus for R&D to ensure the creation of comprehensive product development plans from concept to launch 
    • Develop actionable plans with anticipate regulatory requirements and timelines to support validation and labeling efforts 
    • Provide timely product development requirements to operations which will support scaling infrastructure and capacity to support new product/market needs.  
    • Experience writing and implementing research protocols, reviewing and interpreting data, preparation of study reports, data analysis and presentation of data to internal and external audiences.
    • Ability to work in a matrix environment with other departments to include Project Management, Regulatory Affairs and Medical Affairs.
    • Excellent oral, written and personal communication skills.
    • Strong clinical research, leadership and management experience
    • Demonstrated experience leading collaborations with RA, QA, R&D, Medical and Commercial to successful product launch.  
    • Define and manage external partnership(s) including face to face meeting with global thought leaders
    • Interact with therapeutic partners to inform appropriate product requirements 
    • Serve as subject matter expert across the clinical portfolio to support business objectives
    • Expert communication of data in presentations at scientific conferences, either local, regional, or international
    • Create, support, present medical and scientific educational content supporting strategic plans
    • Exemplifies transparency and promotes quality of science
    • Liaise with Business Development and research functions to maximize the scope of new product development plans


    • Advanced degree in Life Sciences: PhD, MD, or MD PhD 
    • Strong technical background in molecular biology, genomics, next generation sequencing
    • >7 years of experience leading IVD and CLIA product development
    • Research experience in hematology, oncology or immunology with a demonstrated understanding of clinical trials addressing diagnosis, treatment of disease
    • Understanding of running clinical trials from study concept to publication
    • Excellent leadership experience in a matrix environment
    • Effective communication skills
    • Good interpersonal relationship building/maintenance
    • Ability to establish relationships and high-level customers
    • Strong presentation skills are very important
    • Excited about an early stage company environment that may require greater self-sufficiency.
    • Travel is required

please email CV to jobs@tseworldwide.com


Associate Director of Business Development and Strategy- San Francisco

Associate Director of Business Development and Strategy- San Francisco

We have a unique opportunity to join a growing Bay Area biotech.

This position will report to the CEO and will help or lead with:

  • Market Assessments
  • BD Opportunities
  • Liaise with Scientific leadership and Project Management as they enter phIII study


This candidate must have strong modeling skills and will be counted on to handle much of the granular work.

For more information, please send email to jobs@tseworldwide.com

Vice President, Personalized Medicine

We have multiple opportunities for Senior scientists to lead the next wave of cancer R&D for this client.

Ideal candidates have a PhD, have lead teams in product development and deep biomarker expertise.

To set up an exploratory, discussion, please email jobs@tseworldwide.com


Director, Medical Affairs – Immuno-Oncology

  • MD, Board Certification in Oncology/Hematology or Pediatric Oncology/Hematology.
  • Immuno-oncology treatment expertise
  • Industry experience in Medical Affairs or Clinical Development.
  • Opportunities with clients in NJ, PA, MA, CA and WA

Please send message to jobs@tseworldwide.com for client disclosures

Head of US Market Access, Value and Pricing Practice Lead

We have a tremendous opportunity (or opportunities) to join the premier “top tier” Management Consultancy as they continue to build a US Market Access, Value and Pricing division.  There is an existing group in place that has been extraordinarily successful with big pharma and now they are working to build off of this success. Please contact me for more details!