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Chief Medical Officer – Antibody Drug Conjugates

Chief Medical Officer (CMO) ADCs / Bispecifics/ Oncology

Hybrid

San Francisco/Bay Area, CA

Job Description

A high-growth VC-backed biotech specializing in Antibody Drug Conjugates (ADCs)  is seeking a Chief Medical Officer (CMO) to lead clinical and regulatory strategy, driving the development of cutting-edge therapies from IND through regulatory approval.

This is a unique opportunity for a clinical development leader to shape the success of a pioneering biotech at the forefront ADCs in cancer therapeutics.

Key Responsibilities

  • Define and oversee the clinical development strategy for a first-in-class pipeline.
  • Lead IND, CTA, and regulatory filings, engaging with FDA, EMA, and global health authorities.
  • Direct Phase I-III clinical trials, ensuring scientific and operational excellence.
  • Collaborate with R&D and translational medicine teams to optimize biomarker-driven trial design.
  • Represent the company at scientific conferences, investor meetings, and key industry events.
  • Partner with BD and Commercial teams on strategic partnerships and future market planning.

Candidate Profile

  • MD (or MD/PhD) with 10+ years of experience in clinical development.
  • Extensive experience in Oncology drug development, including Bispecifcs, T-Cell Engagers, Immune Modulators
  • Proven track record of advancing oncology assets from early-phase trials through regulatory approval.
  • Strong experience in regulatory interactions (FDA, EMA) and global trial execution.
  • Ability to thrive in a VC-backed, high-growth biotech environment.

Qualified candidates should send CV and cover letter to jobs@tseworldwide.com